Both Virgil van Dijk and Thiago Alcantara have been taken to hospital for scans on the injuries they sustained in Liverpool's 2-2 draw against Everton.
Van Dijk lasted just ten minutes in the game before he was forced off after Toffees goalkeeper Jordan Pickford clattered into him with a late challenge as he looked to get on the end of a cross.
Then, in the last minute, Richarlison was sent off for a reckless late tackle on Thiago.
The Spanish midfielder managed to finish the game, but has reportedly suffered swelling on his leg.
It remains to be seen just how serious both players' injuries are, but Reds boss Jurgen Klopp appeared pessimistic when he spoke about the two at full-time.
On Thiago, he said: "The red card from Richarlison, it's not only a red card for Everton it's a massive foul on Thiago as well.
"Thiago has a proper knock there, he has ice now, we don't know what he has, it looks not good, to be honest."
On Van Dijk, he added: "It's not good. Virgil plays with pain but he couldn't play on. Not good."
Klopp also appeared far from pleased with Pickford's challenge, along with some of the refereeing decisions in the match saying: "Pickford kicks him completely. I need to watch it back.
"I've seen the disallowed goal at the end and in the picture I saw it wasn't offside. Can someone explain that to me?"
Both players would be a huge miss if they are ruled out for a significant amount of time, with the fixtures coming thick and fast for Liverpool.
They start their Champions League campaign with a game against Ajax on Wednesday, and then take on Sheffield United in the Premier League on Saturday.
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